7,47393 % | Loomis, Sayles & Company, L.P. | 1.082.225 | -34.259 | 31/12/2023 |
6,60829 % | ArrowMark Colorado Holdings, LLC | 956.881 | -9.115 | 31/12/2023 |
5,33810 % | Sofinnova Investments, Inc | 772.957 | 29.663 | 31/12/2023 |
49,38416 % | Viking Global Investors LP | 7.150.826 | 0 | 31/12/2023 |
4,91961 % | Capital Research Global Investors | 712.360 | -509.361 | 31/12/2023 |
4,78577 % | BofA Global Research (US) | 692.980 | 577.231 | 31/12/2023 |
4,74696 % | Geode Capital Management, L.L.C. | 687.360 | 41.201 | 31/12/2023 |
4,13161 % | Forsyth Douglas | 598.257 | 0 | 21/2/2024 |
32,62574 % | RA Capital Management, LP | 4.724.207 | 0 | 31/12/2023 |
3,71522 % | PFM Health Sciences, LP | 537.964 | 249.347 | 31/12/2023 |
3,00725 % | Russell Investments Trust Company | 435.450 | -23.606 | 31/12/2023 |
29,39298 % | Perceptive Advisors LLC | 4.256.104 | 0 | 31/12/2023 |
22,61258 % | Kayyem (Jon Faiz) | 3.274.301 | 0 | 21/2/2024 |
21,03352 % | Lappe Mark | 3.045.654 | 0 | 21/2/2024 |
17,06906 % | BlackRock Institutional Trust Company, N.A. | 2.471.600 | 179.080 | 31/12/2023 |
16,26763 % | Eckelman (Brendan P) | 2.355.553 | 0 | 21/2/2024 |
16,01227 % | Woodline Partners LP | 2.318.576 | 793.661 | 31/12/2023 |
12,91364 % | The Vanguard Group, Inc. | 1.869.895 | 84.512 | 31/12/2023 |
12,08831 % | TCG Crossover Management, LLC | 1.750.387 | 0 | 31/12/2023 |
11,29645 % | State Street Global Advisors (US) | 1.635.726 | 18.955 | 31/12/2023 |
10,56630 % | Vestal Point Capital, LP | 1.530.000 | 1.530.000 | 31/12/2023 |
10,15131 % | Fidelity Management & Research Company LLC | 1.469.909 | -47.686 | 31/12/2023 |
1,95010 % | Northern Trust Investments, Inc. | 282.375 | 11.557 | 31/12/2023 |
1,83503 % | Morgan Stanley & Co. LLC | 265.712 | -80.617 | 31/12/2023 |
1,80289 % | Millennium Management LLC | 261.058 | 228.730 | 31/12/2023 |
1,75993 % | Citadel Advisors LLC | 254.838 | 12.028 | 31/12/2023 |
1,58747 % | Charles Schwab Investment Management, Inc. | 229.866 | 17.762 | 31/12/2023 |
1,56458 % | Sphera Funds Management Ltd. | 226.551 | -29.820 | 31/12/2023 |
1,51036 % | Two Sigma Investments, LP | 218.700 | -299.170 | 31/12/2023 |
1,15858 % | Platinum Asset Management | 167.763 | -61.273 | 31/12/2023 |
1,00413 % | Wellington Management Company, LLP | 145.398 | -29.501 | 31/12/2023 |
0,94149 % | Wetherby Asset Management LLC | 136.328 | 0 | 31/12/2023 |
0,93280 % | Candriam Belgium S.A. | 135.069 | -20.000 | 31/12/2023 |
0,91091 % | Hightower Advisors, LLC | 131.900 | 0 | 31/12/2023 |
0,90673 % | Schroder Investment Management Ltd. (SIM) | 131.295 | -106.148 | 31/12/2023 |
0,84472 % | Meridian Wealth Advisors, LLC | 122.315 | 0 | 31/12/2023 |
0,75913 % | Polen Capital Management, LLC | 109.922 | -50.737 | 29/2/2024 |
0,73339 % | Susquehanna International Group, LLP | 106.195 | 77.242 | 31/12/2023 |
0,71302 % | Rafferty Asset Management LLC | 103.246 | -12.582 | 31/12/2023 |
0,70289 % | Goldman Sachs & Company, Inc. | 101.778 | -10.302 | 31/12/2023 |
0,69923 % | abrdn Investments Limited | 101.249 | 80.950 | 31/3/2024 |
0,69061 % | Logos Global Management LLC | 100.000 | 100.000 | 31/12/2023 |
0,65608 % | Caption Management, LLC | 95.000 | 95.000 | 31/12/2023 |
0,62095 % | BNY Mellon Asset Management | 89.914 | 6 | 31/12/2023 |
0,62001 % | BlackRock Investment Management, LLC | 89.778 | -2.352 | 31/12/2023 |
0,61692 % | Schonfeld Strategic Advisors LLC | 89.330 | 89.330 | 31/12/2023 |
0,61371 % | Barclays Bank PLC | 88.865 | 25.688 | 31/12/2023 |
0,61115 % | BlackRock Financial Management, Inc. | 88.494 | -2.412 | 31/12/2023 |
0,57545 % | Nuveen LLC | 83.325 | -5.938 | 31/12/2023 |
0,55791 % | UBS Financial Services, Inc. | 80.785 | 42.782 | 31/12/2023 |
0,50523 % | Exome Asset Management LLC | 73.158 | 73.158 | 31/12/2023 |
0,49371 % | AllianceBernstein L.P. | 71.489 | -20.040 | 31/12/2023 |
0,38794 % | Ensign Peak Advisors, Inc. | 56.173 | 0 | 31/12/2023 |
0,37862 % | BlackRock Advisors (UK) Limited | 54.824 | 2.537 | 31/3/2024 |
0,35499 % | Goldman Sachs Asset Management, L.P. | 51.402 | 4.013 | 31/12/2023 |
0,33941 % | Rhumbline Advisers Ltd. Partnership | 49.147 | 322 | 31/12/2023 |
0,33459 % | Birchview Capital, LP | 48.448 | -22.000 | 31/12/2023 |
0,32062 % | HAP Trading, LLC | 46.426 | 46.426 | 31/12/2023 |
0,31176 % | BlackRock Asset Management Ireland Limited | 45.143 | 3.702 | 31/12/2023 |
0,30863 % | Citi Investment Research (US) | 44.690 | -4.554 | 31/12/2023 |
0,30438 % | Gyon Technologies Capital Management, LP | 44.074 | 44.074 | 31/12/2022 |
0,30356 % | State of Wisconsin Investment Board | 43.956 | -8.926 | 31/12/2023 |
0,28298 % | IndexIQ Advisors LLC | 40.976 | -1.568 | 31/3/2024 |
0,27969 % | Qube Research & Technologies Ltd | 40.499 | 40.499 | 31/12/2023 |
0,27032 % | Invesco Capital Management LLC | 39.143 | 31.795 | 31/12/2023 |
0,26727 % | Schweizerische Nationalbank | 38.700 | -18.900 | 31/12/2023 |
0,26206 % | Jane Street Capital, L.L.C. | 37.946 | -4.369 | 31/12/2023 |
0,24766 % | Simplex Trading, LLC | 35.861 | 35.225 | 31/12/2023 |
0,24171 % | Ghost Tree Capital, LLC | 35.000 | 0 | 31/12/2023 |
0,22864 % | Alps Advisors, Inc. | 33.107 | 33.107 | 31/12/2023 |
0,22304 % | Assenagon Asset Management S.A. | 32.296 | 2.344 | 29/2/2024 |
0,21176 % | Parametric Portfolio Associates LLC | 30.663 | -5.110 | 31/12/2023 |
0,21106 % | Hennion & Walsh Asset Management, Inc. | 30.561 | 744 | 31/3/2024 |
0,21046 % | Northern Trust Global Investments | 30.474 | -5.346 | 31/12/2023 |
0,19510 % | Alpine Associates Management Inc. | 28.251 | 12.959 | 31/3/2024 |
0,18232 % | Deka Vermögensmanagement GmbH | 26.400 | 0 | 31/12/2023 |
0,18232 % | Deka Investment GmbH | 26.400 | 0 | 31/12/2022 |
0,16989 % | Bellevue Asset Management AG | 24.600 | -24.200 | 31/12/2023 |
0,16700 % | Mellon Investments Corporation | 24.181 | 96 | 31/12/2023 |
0,16427 % | Wilmington Trust Investment Advisors, Inc. | 23.786 | -4.647 | 31/12/2023 |
0,16240 % | Campbell & Company, Inc. | 23.516 | 23.516 | 31/12/2023 |
0,15988 % | California State Teachers Retirement System | 23.150 | -7.554 | 31/12/2023 |
0,15689 % | JPMorgan Private Bank (United States) | 22.718 | 2.425 | 31/12/2023 |
0,15305 % | UBS Asset Management (Switzerland) | 22.161 | 0 | 31/12/2023 |
0,14153 % | Mirae Asset Global Investments (USA) LLC | 20.494 | 1.331 | 31/12/2023 |
0,13634 % | Credit Suisse Funds AG | 19.742 | -2.364 | 31/12/2023 |
0,13357 % | Alaethes Wealth LLC | 19.341 | 0 | 31/12/2023 |
0,13305 % | Legal & General Investment Management Ltd. | 19.265 | -2.896 | 31/12/2023 |
0,13249 % | JP Morgan Asset Management | 19.185 | -299.409 | 31/12/2023 |
0,12693 % | Tudor Investment Corporation | 18.379 | -3.331 | 31/12/2023 |
0,12565 % | MetLife Investment Management, LLC | 18.194 | 0 | 31/12/2023 |
0,11826 % | ProFund Advisors LLC | 17.124 | -2.622 | 31/12/2023 |
0,11789 % | SunAmerica Asset Management, LLC | 17.071 | -69 | 31/12/2023 |
0,11213 % | Prelude Capital Management, LLC | 16.236 | 3.015 | 31/12/2023 |
0,10535 % | Aperio Group, LLC | 15.255 | 3.062 | 31/12/2023 |
0,10359 % | Soleus Capital Management, L.P. | 15.000 | -534.183 | 31/12/2023 |
0,10332 % | DWS Investments UK Limited | 14.961 | -418 | 31/12/2023 |
0,10124 % | RS Crum INC | 14.659 | 0 | 31/12/2023 |
0,09985 % | LMR Partners LLP | 14.458 | 0 | 31/12/2023 |
0,09814 % | Wells Fargo Advisors | 14.211 | -550 | 31/12/2023 |